【Abstract】 Objective Compare the control efficacy and control cost of two different anticoagulant rodenticides against Mongolian gerbil (Meriones unguiculatus). Methods Tests were carried out from September to October of 2007 in Abage county. The control efficacy and control cost of 4 different bait treatments methods were calculated. Results The results showed that the killing efficiency of bromadiolone poison baits to M.unguiculatus was 59.18%, increasing by 6.95% than that of sodium diphacinone (52.23%). Taking the control efficacy and control cost into account, bromadiolone poison baits put at 10 m intervals was the optimum method, and its cost was￥22.05/hm2. Conclusion Compared to sodium diphacinone, bromadiolone, with the characteristics of high?efficiency and safety, is used for the control of  M.unguiculatus.